<p>It's easy for a business to go beyond the boundaries of its main market and get excited about branching out into these new opportunities. While these opportunities are enticing the business must stay true to its focus and continue to mine the gold contained in its core product/offering.
<br /> <br /> You need look only at a couple of examples from history to know this is true.<br /> <br /> The Roman Empire was perhaps the greatest organization ever. It's only really rivaled by Alexander the Great's empire and perhaps the Persian Empire. One of the big things that brought the Roman empire down was a disease from within.<br /> <br /> There were many outside that factors like a communicable disease which wiped out 25% of the population, a seemingly endless line of poor emperor leaders, civil war, and an ever widening chasm between the rich and the poor which was 10 times greater than what we see today.<br /> <br /> In addition, there were always lots of cults and pagan religions the Romans were tolerant of. Then Christianity started to come to the forefront in the third and fourth centuries A.D. and caused a crisis of identity in the Roman Empire.<br /> <br /> This Crisis of identity sent people searching for religion and faith and caused them to question the b
enefits of the Roman empire and its rule. This was probably the most damaging thing that led to the end of the Empire.
<br /> This identity crisis was the silent internal killer which brought down the empire.<br /> <br /> So you need to maintain the culture of your business and its identity. Everyone working in your business needs to believe in the identity and what the business is doing to bring value to your marketplace.<br /> <br /> When that starts to come into question it is the beginning of the end for your business. IBM had a huge crisis of identity 30 to 40 years ago but they were able to remake themselves and adapt to the marketplace thus saving their business.<br /> <br /> Plan for your growth and maintain the strength of your identity. Don't let your business get to the point of IBM where it needs saving. It's easy to take a look at and learn from the mistakes of history that brought some of the greatest organizations down.<br /> <br /> People, including your business employees and partners and suppliers, all need something to believe in a higher purpose to strive for. Religious o
rganizations know this and are good at it.<br /> <br /> It's time for you to put this concept into practice in your business.<br /> <br /> Keep organizational identity strong and clear and so will your business be.</p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
vineri, 17 mai 2013
joi, 16 mai 2013
Sir Peter Alexander Ustinov ? Renaissance Funny Man
<p><strong> <strong>Sir Peter Ustinov</strong></strong> was one of Britain's greatest icons and is recognised worldwide as one of the greatest comic actors, dramatist, director, writer of the 20th Century. I thought it would be interesting to write the story of this famous icon from his birth in London on April 26th 1921 to his present day status as a great British Icon.</p>
<p>He was born Peter Alexander Freiherr von Ustinov on April 16, 1921, in Swiss Cottage, London, England. Ustinov was of Russian, German, French, Italian and Ethiopian descent, with ancestral connections to Russian nobility as well as the Ethiopian Royal Family. His grandmother, Magdalena, was daughter of a Swiss military engineer and Ethiopian princess. His father, Iona von Ustinov, also known as "Klop" in Russian and Yiddish, was a pilot in Luftwaffe during the First World War. In 1919 he joined his mother and sister in St. Petersburg, Russia. There he met artist Nadia Benois who worked for the Imperial Mariinsky Ballet and Opera House in St. Petersburg. In 1920, in a modest and discrete ceremony at a Russian-German Church in St. Petersburg, Ustinov's father married Nadia Benois. Later, when she was 7 months pregnant with Peter Ustinov, the couple emigrated from Russia in 1921, in the aftermath of the Communist Revolution.<br /><br />Young Peter Ustinov was brought up in a
multi-lingual family, he was fluent in Russian, French, Italian, and German, and also was a native English speaker. He attended the Westminster College in 1934-37, took the drama and acting class under Michel St. Denis at the London Theatre Studio, 1937-39, and made his stage debut in 1938, in a theatre in Surrey. In 1939, he made his London stage debut in a revue sketch, then had regular performances with Aylesbury Repertory Company. In 1940 he made his film debut in Hullo Fame (1940).<br /><br />From 1942-46 Ustinov served as a private soldier with the British Army's Royal Sussex Regiment, during the Second World War. He was batman for David Niven and the two became life-long friends. Ustinov spent most of his service working with the Army Cinema Unit, where he was involved in making recruitment films, wrote plays, and appeared in three films as actor. At that time he wrote and directed his film, The Way Ahead (1944) (aka.. The Immortal Battalion).<br /><br />Eventually, U
stinov made a stellar film career as actor, director, and writer, appearing in more than 100 film and television productions. He was awarded two Oscars for Best Supporting Actor, one for his role in Spartacus (1960) and one for his role in Topkapi (1964); and received two more Oscar nominations as an actor and writer. During the 1970s he had a slowdown in his career, before making a comeback as Hercule Poirot in Death on The Nile (1978) by director John Guillermin. In the 1980s, Ustinov reprised the Poirot role in several subsequent television movies and theatrical films, such as Evil under the Sun (1982) and Appointment with Death (1988). Later he appeared as a sympathetic doctor in the disease thriller Lorenzo's Oil (1992).<br /><br />Ustinov's effortless style, his expertise in dialectal and physical comedy made him a regular guest of numerous talk shows and late night comedians. His witty and multi-dimensional humour was legendary, and he later published a collection of
his jokes and quotations, summarizing his wide popularity as a raconteur. He was also an internationally acclaimed TV journalist. For one of his projects Ustinov covered over one hundred thousand miles and visited more than 30 Russian cities during the making of his well-received BBC television series 'Peter Ustinov's Russia'.<br /><br />In his autobiographical books, such as 'Dear Me' (1977) and 'My Russia' (1996), Ustinov revealed a wealth of thoughtful and deep observations about how his life and career was formed by his rich multi-cultural and multi-ethnic background. Ustinov wrote and directed numerous stage plays, having success with presenting his plays in several countries, such as his 'Photofinish' had acclaimed staging in New York, London, and St. Petersburg, Russia, starring Elena Solovey and Petr Shelokhonov among other actors.<br /><br />Outside of his film and acting professions, Ustinov served as a roving ambassador for the United Nations Children's Fund. He w
as knighted Sir Peter Ustinov in 1990. From 1971 to his death in 2004, Ustinov lived in his own Chteau in the village of Bursins, Vaud, Switzerland, He died of a heart failure on March 28, 2004, in Genolier, Vaud, Switzerland. His funeral service was held at Geneva's historic cathedral of St. Pierre, and he was laid to rest in the village cemetery of Bursins, Switzerland. He was survived by three daughters, Tamara, Pavla, and Andrea, and son, Igor Ustinov.</p>
<p>"I am an international citizen conceived in Russia, born in England, working in Hollywood, living in Switzerland, and touring the World" said Peter Ustinov.</p>
<p><strong><em>Please visit my Funny Animal Art Prints Collection @ </em></strong></p>
<p><strong><strong><em>My other website is called Directory of British Icons: </em></strong></strong><strong><em></em></strong></p>
<p><strong><em>The Chinese call Britain 'The Island of Hero's' which I think sums up what we British are all about. We British are inquisitive and competitive and are always looking over the horizon to the next adventure and discovery. </em></strong></p>
<p><strong><strong><em>Please feel free to vote for my article by scrolling down the page and clicking Stars.</em></strong></strong></p>
<p><strong><strong><em>Copyright 2010 Paul Hussey. All Rights Reserved.</em></strong></strong></p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
<p>He was born Peter Alexander Freiherr von Ustinov on April 16, 1921, in Swiss Cottage, London, England. Ustinov was of Russian, German, French, Italian and Ethiopian descent, with ancestral connections to Russian nobility as well as the Ethiopian Royal Family. His grandmother, Magdalena, was daughter of a Swiss military engineer and Ethiopian princess. His father, Iona von Ustinov, also known as "Klop" in Russian and Yiddish, was a pilot in Luftwaffe during the First World War. In 1919 he joined his mother and sister in St. Petersburg, Russia. There he met artist Nadia Benois who worked for the Imperial Mariinsky Ballet and Opera House in St. Petersburg. In 1920, in a modest and discrete ceremony at a Russian-German Church in St. Petersburg, Ustinov's father married Nadia Benois. Later, when she was 7 months pregnant with Peter Ustinov, the couple emigrated from Russia in 1921, in the aftermath of the Communist Revolution.<br /><br />Young Peter Ustinov was brought up in a
multi-lingual family, he was fluent in Russian, French, Italian, and German, and also was a native English speaker. He attended the Westminster College in 1934-37, took the drama and acting class under Michel St. Denis at the London Theatre Studio, 1937-39, and made his stage debut in 1938, in a theatre in Surrey. In 1939, he made his London stage debut in a revue sketch, then had regular performances with Aylesbury Repertory Company. In 1940 he made his film debut in Hullo Fame (1940).<br /><br />From 1942-46 Ustinov served as a private soldier with the British Army's Royal Sussex Regiment, during the Second World War. He was batman for David Niven and the two became life-long friends. Ustinov spent most of his service working with the Army Cinema Unit, where he was involved in making recruitment films, wrote plays, and appeared in three films as actor. At that time he wrote and directed his film, The Way Ahead (1944) (aka.. The Immortal Battalion).<br /><br />Eventually, U
stinov made a stellar film career as actor, director, and writer, appearing in more than 100 film and television productions. He was awarded two Oscars for Best Supporting Actor, one for his role in Spartacus (1960) and one for his role in Topkapi (1964); and received two more Oscar nominations as an actor and writer. During the 1970s he had a slowdown in his career, before making a comeback as Hercule Poirot in Death on The Nile (1978) by director John Guillermin. In the 1980s, Ustinov reprised the Poirot role in several subsequent television movies and theatrical films, such as Evil under the Sun (1982) and Appointment with Death (1988). Later he appeared as a sympathetic doctor in the disease thriller Lorenzo's Oil (1992).<br /><br />Ustinov's effortless style, his expertise in dialectal and physical comedy made him a regular guest of numerous talk shows and late night comedians. His witty and multi-dimensional humour was legendary, and he later published a collection of
his jokes and quotations, summarizing his wide popularity as a raconteur. He was also an internationally acclaimed TV journalist. For one of his projects Ustinov covered over one hundred thousand miles and visited more than 30 Russian cities during the making of his well-received BBC television series 'Peter Ustinov's Russia'.<br /><br />In his autobiographical books, such as 'Dear Me' (1977) and 'My Russia' (1996), Ustinov revealed a wealth of thoughtful and deep observations about how his life and career was formed by his rich multi-cultural and multi-ethnic background. Ustinov wrote and directed numerous stage plays, having success with presenting his plays in several countries, such as his 'Photofinish' had acclaimed staging in New York, London, and St. Petersburg, Russia, starring Elena Solovey and Petr Shelokhonov among other actors.<br /><br />Outside of his film and acting professions, Ustinov served as a roving ambassador for the United Nations Children's Fund. He w
as knighted Sir Peter Ustinov in 1990. From 1971 to his death in 2004, Ustinov lived in his own Chteau in the village of Bursins, Vaud, Switzerland, He died of a heart failure on March 28, 2004, in Genolier, Vaud, Switzerland. His funeral service was held at Geneva's historic cathedral of St. Pierre, and he was laid to rest in the village cemetery of Bursins, Switzerland. He was survived by three daughters, Tamara, Pavla, and Andrea, and son, Igor Ustinov.</p>
<p>"I am an international citizen conceived in Russia, born in England, working in Hollywood, living in Switzerland, and touring the World" said Peter Ustinov.</p>
<p><strong><em>Please visit my Funny Animal Art Prints Collection @ </em></strong></p>
<p><strong><strong><em>My other website is called Directory of British Icons: </em></strong></strong><strong><em></em></strong></p>
<p><strong><em>The Chinese call Britain 'The Island of Hero's' which I think sums up what we British are all about. We British are inquisitive and competitive and are always looking over the horizon to the next adventure and discovery. </em></strong></p>
<p><strong><strong><em>Please feel free to vote for my article by scrolling down the page and clicking Stars.</em></strong></strong></p>
<p><strong><strong><em>Copyright 2010 Paul Hussey. All Rights Reserved.</em></strong></strong></p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
miercuri, 15 mai 2013
Most common Diseases of Ages of 50+: Gout Treatments In conventional medicine perspective
<p><strong>Musculoskeletal disorders</strong> (MSDs) is medical condition mostly caused by work related occupations and working environment, affecting patients' muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. <strong>Musculoskeletal pain</strong> was reported by 57% of those interviewed. A major restriction of<strong> joint movement </strong>range was frequent in the <strong>shoulder</strong> but uncommon in other joints. A <strong>shoulder disorder</strong> was found in 27% of subjects, <strong>rheumatoid arthritis</strong> in 1% and <strong>osteoarthritis</strong> (OA) of the hand, hip, and knee in five, seven, and 18% of subjects, respectively. Disability was frequent: a <strong>walking distance </strong>of < 500 m was found in 60% and ADL dependency in 40% of the group. Factors related to one or both of these disability measures included
female gender, hip and knee OA,<strong> impaired vision, cognitive impairment and neurological disease</strong>(1a).<br /> <br /> <strong>Types of Musculo-Skeletal disorders in elder(2a)</strong><br /> 1. Osteoarthritis<br /> 2. Gout<br /> 3. Rheumatoid Arthritis<br /> 4. Polymalagia Arthritis<br /> 5. Cervical myleopathy and spinal canal stenosis<br /> 6. Osteoporosis<br /> 7. Low back pain<br /> 8. Fibromyalgia <br /> <br /> <strong>Gout</strong><br /> <strong>I. Gout </strong>mostly effected one joint is defined as a acute and recurrent condition of arthritis as a result of uric acid builds up in blood cause of joint inflammation.<br /> <br /><br /> <strong>VI. Treatments</strong><br /> A. In conventional medicine perspective<br /> <strong>A.1. Acetaminophen</strong><br /> <strong>a. Acetaminophen such as Tylenol can help to relive the pain of </strong><strong>Gout. </strong><br /> <strong><strong>b. Side effects if overdose are not limit to</strong></strong><br /> <stro
ng>b.1. Nausea and vomiting</strong><br /> <strong>b.2. Appetite loss</strong><br /> <strong>b.3. Sweating</strong><br /> <strong>b.4. Diarrhea</strong><br /> <strong>b.5. Irritability</strong><br /> <strong>b.6. Abdominal pain</strong><br /> <strong>b.7. Etc.</strong><br /> <br /> <strong>A.2. </strong><strong>In the study of </strong>Gout--what are the treatment options? indicated that The options available for the treatment of acute gout (18)are </p>
<strong>1. NSAIDs </strong>
a. NSAIDs are commonly prescribed to control gout attacks in patients with hyperuricaemia.
b. <strong>Side effects are not limit to</strong><br /> <strong>Dr. </strong>Bjarnason I, and the research team at King's College School of Medicine and Dentistry, in the study of Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans, showed that Ingested NSAIDs may cause <strong>a nonspecific colitis (in particular, fenemates)</strong>, and many patients with collagenous colitis are taking NSAIDs. <strong>Large intestinal ulcers, bleeding, and perforation</strong> are occasionally due to NSAIDs. NSAIDs may cause relapse of <strong>classic inflammatory bowel disease</strong> and contribute to serious complications of <strong>diverticular disease (fistula and perforation)</strong>. NSAIDs may occasionally cause <strong>small intestinal perforation, ulcers, and strictures requiring surgery</strong>. NSAIDs, however, frequently cause <strong>small intestinal inflammatio</strong>n, and the associated complications of blood loss and protei
n loss may lead to difficult management problems. The pathogenesis of NSAID enteropathy is a multistage process involving <strong>specific biochemical and subcellular organelle damage</strong> followed by a relatively nonspecific tissue reaction. The various possible treatments of NSAID-induced enteropathy (sulphasalazine, misoprostol, metronidazole) have yet to undergo rigorous trials(19).
<strong>2. Colchicine</strong>
a. Colchicine, used for a long period in gout, was approved for the first time in 2009 by the FDA for the prophylaxis and the treatment of acute attack, on the basis of a pivotal trial that showed the efficacy in the very short term - that is 24 h of a well-tolerated, low-dose regimen of Colcrys (colchicine, URL Pharma, Philadelphia, USA) to reduce pain in patients with acute gout - when given early(20).
b. Side effects are not limit to
1. Diarrhea
2. Dizziness
3. Flushing
4. Hair loss
5. Headache
6. Loss of appetite
7. Nausea; sore gums
8. Stomach pain
9. Vomiting
10. Etc.
<strong>3. Corticosteroids </strong>
a. researchers suggested that Systemic corticosteroids could be used in severe polyarticular flares. Anti-IL1should provide a therapeutic alternative for severe cortico dependant gout with tophus. To prevent acute flares and reduce tophus volume, uric acid serum level should be reduced and maintained below 60mg/L (360mol/L).
b. Side effects are not limit to
b.1. Stomach irritation
b.2. Rapid heartbeat
b.3. Nausea
b.4. Insomnia
b.5. A metallic taste in the mouth
b.6. Etc.
4. Adrenocorticotropic hormone (ACTH) and
a. In the study of Effects of adrenocorticotropic hormone (ACTH) in gout by Alexander B. Gutman, M.D.1, T.F. Y, M.D indicated that ACTH effected a very rapid and satisfactory response in the local and systemic manifestations of acute gout in seven of eleven cases treated, including one patient refractory to colchicine. ACTH therefore appears to be a useful agent in the therapy of acute gout. In many of these patients, however, ACTH was not convincingly superior to colchicine, and in four instances colchicine terminated attacks responding unsatisfactorily to ACTH. Unlike colchicine, ACTH is not suitable for prophylactic use in the prevention of acute gouty attacks(20).
<strong>b. Side effects are not limit to </strong>
In the study of 162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused <strong>pronounced side effects, and the mortality was 4.9%</strong>. The most common complications wer<strong>e infections: septic infections, pneumonias, and urinary and gastrointestinal infections. Other side effects were arterial hypertension (11), osteoporosis (2), hypokalaemic alkalosis (2), and other marked electrolyte disturbances (10). In children necropsy showed fresh intracerebral haemorrhages</strong>. Four children developed oliguria and hyperkalaemia during and after withdrawal of ACTH. One of them had tubular necrosis confirmed by renal biopsy. Infections were significantly more common with large doses (120 units) of ACTH than with small ones (40 units). It is concluded that side effects, even severe ones, are more common during trea
tment than had been assumed(21).
<strong>5. Intra-articular corticosteroids</strong>
a. Intraarticular steroid injections are injected directly into an affected joint to improve joint function.
b. Side effects are not limit to
b.1. Infection
b.2. Facial flushing
b.3. Local skin atrophy and depigmentation
b.4. Crystalline synovitis
b.5. Allergic reaction
b.6. Uterine haemorrhage
b.7. Etc.
The most important determinant of therapeutic success is not which anti-inflammatory agent is chosen, but rather how soon therapy is initiated and that the dose be appropriate.
<strong>b. Side effects are not limit to</strong>
b.1. Constipation
b.2. Diarrhea
b.3. Dizziness
b.4. Drowsiness
b.5. Headache
b.6. Heartburn
b.7. Nausea
b.8. Stomach upset
b.9. Etc.
<p>7. Etc.</p>
<p>For common types of diseases of Ages of 50+, please visit /p/better-of-living-health-50-over.html<br /> <br /> For other health article, visit <br /></p>
<p>Sources can be found at /2012/07/most-common-diseases-of-ages-of-50_15.html</p>
<br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
female gender, hip and knee OA,<strong> impaired vision, cognitive impairment and neurological disease</strong>(1a).<br /> <br /> <strong>Types of Musculo-Skeletal disorders in elder(2a)</strong><br /> 1. Osteoarthritis<br /> 2. Gout<br /> 3. Rheumatoid Arthritis<br /> 4. Polymalagia Arthritis<br /> 5. Cervical myleopathy and spinal canal stenosis<br /> 6. Osteoporosis<br /> 7. Low back pain<br /> 8. Fibromyalgia <br /> <br /> <strong>Gout</strong><br /> <strong>I. Gout </strong>mostly effected one joint is defined as a acute and recurrent condition of arthritis as a result of uric acid builds up in blood cause of joint inflammation.<br /> <br /><br /> <strong>VI. Treatments</strong><br /> A. In conventional medicine perspective<br /> <strong>A.1. Acetaminophen</strong><br /> <strong>a. Acetaminophen such as Tylenol can help to relive the pain of </strong><strong>Gout. </strong><br /> <strong><strong>b. Side effects if overdose are not limit to</strong></strong><br /> <stro
ng>b.1. Nausea and vomiting</strong><br /> <strong>b.2. Appetite loss</strong><br /> <strong>b.3. Sweating</strong><br /> <strong>b.4. Diarrhea</strong><br /> <strong>b.5. Irritability</strong><br /> <strong>b.6. Abdominal pain</strong><br /> <strong>b.7. Etc.</strong><br /> <br /> <strong>A.2. </strong><strong>In the study of </strong>Gout--what are the treatment options? indicated that The options available for the treatment of acute gout (18)are </p>
<strong>1. NSAIDs </strong>
a. NSAIDs are commonly prescribed to control gout attacks in patients with hyperuricaemia.
b. <strong>Side effects are not limit to</strong><br /> <strong>Dr. </strong>Bjarnason I, and the research team at King's College School of Medicine and Dentistry, in the study of Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans, showed that Ingested NSAIDs may cause <strong>a nonspecific colitis (in particular, fenemates)</strong>, and many patients with collagenous colitis are taking NSAIDs. <strong>Large intestinal ulcers, bleeding, and perforation</strong> are occasionally due to NSAIDs. NSAIDs may cause relapse of <strong>classic inflammatory bowel disease</strong> and contribute to serious complications of <strong>diverticular disease (fistula and perforation)</strong>. NSAIDs may occasionally cause <strong>small intestinal perforation, ulcers, and strictures requiring surgery</strong>. NSAIDs, however, frequently cause <strong>small intestinal inflammatio</strong>n, and the associated complications of blood loss and protei
n loss may lead to difficult management problems. The pathogenesis of NSAID enteropathy is a multistage process involving <strong>specific biochemical and subcellular organelle damage</strong> followed by a relatively nonspecific tissue reaction. The various possible treatments of NSAID-induced enteropathy (sulphasalazine, misoprostol, metronidazole) have yet to undergo rigorous trials(19).
<strong>2. Colchicine</strong>
a. Colchicine, used for a long period in gout, was approved for the first time in 2009 by the FDA for the prophylaxis and the treatment of acute attack, on the basis of a pivotal trial that showed the efficacy in the very short term - that is 24 h of a well-tolerated, low-dose regimen of Colcrys (colchicine, URL Pharma, Philadelphia, USA) to reduce pain in patients with acute gout - when given early(20).
b. Side effects are not limit to
1. Diarrhea
2. Dizziness
3. Flushing
4. Hair loss
5. Headache
6. Loss of appetite
7. Nausea; sore gums
8. Stomach pain
9. Vomiting
10. Etc.
<strong>3. Corticosteroids </strong>
a. researchers suggested that Systemic corticosteroids could be used in severe polyarticular flares. Anti-IL1should provide a therapeutic alternative for severe cortico dependant gout with tophus. To prevent acute flares and reduce tophus volume, uric acid serum level should be reduced and maintained below 60mg/L (360mol/L).
b. Side effects are not limit to
b.1. Stomach irritation
b.2. Rapid heartbeat
b.3. Nausea
b.4. Insomnia
b.5. A metallic taste in the mouth
b.6. Etc.
4. Adrenocorticotropic hormone (ACTH) and
a. In the study of Effects of adrenocorticotropic hormone (ACTH) in gout by Alexander B. Gutman, M.D.1, T.F. Y, M.D indicated that ACTH effected a very rapid and satisfactory response in the local and systemic manifestations of acute gout in seven of eleven cases treated, including one patient refractory to colchicine. ACTH therefore appears to be a useful agent in the therapy of acute gout. In many of these patients, however, ACTH was not convincingly superior to colchicine, and in four instances colchicine terminated attacks responding unsatisfactorily to ACTH. Unlike colchicine, ACTH is not suitable for prophylactic use in the prevention of acute gouty attacks(20).
<strong>b. Side effects are not limit to </strong>
In the study of 162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused <strong>pronounced side effects, and the mortality was 4.9%</strong>. The most common complications wer<strong>e infections: septic infections, pneumonias, and urinary and gastrointestinal infections. Other side effects were arterial hypertension (11), osteoporosis (2), hypokalaemic alkalosis (2), and other marked electrolyte disturbances (10). In children necropsy showed fresh intracerebral haemorrhages</strong>. Four children developed oliguria and hyperkalaemia during and after withdrawal of ACTH. One of them had tubular necrosis confirmed by renal biopsy. Infections were significantly more common with large doses (120 units) of ACTH than with small ones (40 units). It is concluded that side effects, even severe ones, are more common during trea
tment than had been assumed(21).
<strong>5. Intra-articular corticosteroids</strong>
a. Intraarticular steroid injections are injected directly into an affected joint to improve joint function.
b. Side effects are not limit to
b.1. Infection
b.2. Facial flushing
b.3. Local skin atrophy and depigmentation
b.4. Crystalline synovitis
b.5. Allergic reaction
b.6. Uterine haemorrhage
b.7. Etc.
The most important determinant of therapeutic success is not which anti-inflammatory agent is chosen, but rather how soon therapy is initiated and that the dose be appropriate.
<strong>b. Side effects are not limit to</strong>
b.1. Constipation
b.2. Diarrhea
b.3. Dizziness
b.4. Drowsiness
b.5. Headache
b.6. Heartburn
b.7. Nausea
b.8. Stomach upset
b.9. Etc.
<p>7. Etc.</p>
<p>For common types of diseases of Ages of 50+, please visit /p/better-of-living-health-50-over.html<br /> <br /> For other health article, visit <br /></p>
<p>Sources can be found at /2012/07/most-common-diseases-of-ages-of-50_15.html</p>
<br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
marți, 14 mai 2013
Scoring System for Plain Chest Radiographs in Patients with Asbestos Related Disease
<p>One interesting study is called, "Methods for the quantitative determination of asbestos and quartz in bulk samples using X-ray diffraction" by M. Taylor - Analyst, 1978, 103, 1009 1020. Here is an excerpt: "Procedures are described for the quantitative determination of the asbestos and -quartz contents of bulk samples by use of X-ray powder diffractometry. The method gives satisfactory results for several different types of asbestos and for mixtures of two or more different types. Problems with sample grinding and preferred-orientation effects have been largely overcome. An effective procedure has been developed for grinding samples to a suitable particle size for accurate quantitative work. This procedure works equally well for all the types of asbestos studied and the sample is intimately mixed with the internal standard, nickel (II) oxide, at the same time. A sample press has been designed that enables the same pressure to be applied to each sample when sample holders
are filled for the diffractometer, giving the same degree of preferred orientation each time. Calibration lines have been calculated for chrysotile, amosite, crocidolite and anthophyllite, and results are given for mixtures containing two or more types of asbestos as well as other commonly occurring minerals.Similar techniques are used to grind samples containing quartz and to mix them with internal standard. Work on both synthetic and real samples is described and results are compared with those obtained by use of an infrared spectroscopic method."</p>
<p>Another interesting study is called, "A new high resolution computed tomography scoring system for pulmonary fibrosis, pleural disease, and emphysema in patients with asbestos related disease." By N A Jarad, P Wilkinson, M C Pearson, R M Rudd - Br J Ind Med 1992;49:73-84. Here is an excerpt: "Abstract - The aim of this study was to describe a scoring system for high resolution computed tomographic (HRCT) scans analogous to the International Labour Office (ILO) scoring system for plain chest radiographs in patients with asbestos related disease. Interstitial fibrosis, pleural disease, and emphysema were scored, the reproducibility and the interobserver agreement using this scoring system were examined, and the extent of the various types of disease was correlated with measurements of lung function. Sixty asbestos workers (five women and 55 men) mean age 59 (range 34-78) were studied. The lungs were divided into upper, middle, and lower thirds. An HRCT score for the extent o
f pleural disease and pulmonary disease in each third was recorded in a way analogous to the International Labour Office (ILO) method of scoring pleural and parenchymal disease on chest radiographs. A CT score for the extent of emphysema was also recorded. Pleural disease and interstitial fibrosis on the plain chest radiographs were assessed according to the ILO scoring system. A chest radiographic score for emphysema analogous to that used for HRCT was also recorded. Two independent readers assigned HRCT scores that differed by two categories or less in 96%, 92%, and 85% compared with 90%, 78%, and 79% of cases for chest radiographs for fibrosis, emphysema, and pleural disease respectively. There was better intraobserver repeatability for the HRCT scores than for the chest radiograph scores for all disorders. Multiple regression analysis showed that scores for interstitial fibrosis, emphysema, and pleural disease on chest radiographs and HRCT correlated to a similar degree
with impairment of lung function."</p>
<p>Another interesting study is called, "Declining Relative Risks for Lung Cancer After Cessation of Asbestos Exposure" by Walker, Alexander M. M.D., Dr. P.H. - June 1984 - Volume 26 - Issue 6. Here is an excerpt: "Abstract All studies that provide follow-up information for workers more than 35 years after initial exposure to asbestos show a declining ratio of observed to expected lung cancer deaths at the end of follow-up. The most parsimonious explanation of this finding is that relative risk for lung cancer begins to decline sometime after cessation of asbestos exposure."</p>
<p>Another interesting study is called, "Scavengers of active oxygen species prevent cigarette smoke-induced asbestos fiber penetration in rat tracheal explants." By A. Churg, J. Hobson, K. Berean, and J. Wright - Am J Pathol. 1989 October; 135(4): 599603. Here is an excerpt: "Abstract - It was previously shown that rat tracheal explants first exposed to cigarette smoke and then to amosite asbestos take up more asbestos fibers than explants exposed to air and asbestos. To examine the mechanism of this process, the same experimental design was followed but test groups were added in which the asbestos was mixed with catalase or superoxide dismutase, scavengers of active oxygen species, or deferoxamine, an iron chelator that prevents formation of hydroxyl radical. All three agents protected against the cigarette smoke effect. Heat inactivated catalase or superoxide dismutase was not protective. These observations indicate that active oxygen species, probably derived from the cig
arette smoke, play a role in smoke-mediated fiber transport into tracheobronchial epithelia."</p>
<p>If you found any of these excerpts interesting, please read the studies in their entirety. We all owe a debt of gratitude to these researchers for their hard work.</p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
are filled for the diffractometer, giving the same degree of preferred orientation each time. Calibration lines have been calculated for chrysotile, amosite, crocidolite and anthophyllite, and results are given for mixtures containing two or more types of asbestos as well as other commonly occurring minerals.Similar techniques are used to grind samples containing quartz and to mix them with internal standard. Work on both synthetic and real samples is described and results are compared with those obtained by use of an infrared spectroscopic method."</p>
<p>Another interesting study is called, "A new high resolution computed tomography scoring system for pulmonary fibrosis, pleural disease, and emphysema in patients with asbestos related disease." By N A Jarad, P Wilkinson, M C Pearson, R M Rudd - Br J Ind Med 1992;49:73-84. Here is an excerpt: "Abstract - The aim of this study was to describe a scoring system for high resolution computed tomographic (HRCT) scans analogous to the International Labour Office (ILO) scoring system for plain chest radiographs in patients with asbestos related disease. Interstitial fibrosis, pleural disease, and emphysema were scored, the reproducibility and the interobserver agreement using this scoring system were examined, and the extent of the various types of disease was correlated with measurements of lung function. Sixty asbestos workers (five women and 55 men) mean age 59 (range 34-78) were studied. The lungs were divided into upper, middle, and lower thirds. An HRCT score for the extent o
f pleural disease and pulmonary disease in each third was recorded in a way analogous to the International Labour Office (ILO) method of scoring pleural and parenchymal disease on chest radiographs. A CT score for the extent of emphysema was also recorded. Pleural disease and interstitial fibrosis on the plain chest radiographs were assessed according to the ILO scoring system. A chest radiographic score for emphysema analogous to that used for HRCT was also recorded. Two independent readers assigned HRCT scores that differed by two categories or less in 96%, 92%, and 85% compared with 90%, 78%, and 79% of cases for chest radiographs for fibrosis, emphysema, and pleural disease respectively. There was better intraobserver repeatability for the HRCT scores than for the chest radiograph scores for all disorders. Multiple regression analysis showed that scores for interstitial fibrosis, emphysema, and pleural disease on chest radiographs and HRCT correlated to a similar degree
with impairment of lung function."</p>
<p>Another interesting study is called, "Declining Relative Risks for Lung Cancer After Cessation of Asbestos Exposure" by Walker, Alexander M. M.D., Dr. P.H. - June 1984 - Volume 26 - Issue 6. Here is an excerpt: "Abstract All studies that provide follow-up information for workers more than 35 years after initial exposure to asbestos show a declining ratio of observed to expected lung cancer deaths at the end of follow-up. The most parsimonious explanation of this finding is that relative risk for lung cancer begins to decline sometime after cessation of asbestos exposure."</p>
<p>Another interesting study is called, "Scavengers of active oxygen species prevent cigarette smoke-induced asbestos fiber penetration in rat tracheal explants." By A. Churg, J. Hobson, K. Berean, and J. Wright - Am J Pathol. 1989 October; 135(4): 599603. Here is an excerpt: "Abstract - It was previously shown that rat tracheal explants first exposed to cigarette smoke and then to amosite asbestos take up more asbestos fibers than explants exposed to air and asbestos. To examine the mechanism of this process, the same experimental design was followed but test groups were added in which the asbestos was mixed with catalase or superoxide dismutase, scavengers of active oxygen species, or deferoxamine, an iron chelator that prevents formation of hydroxyl radical. All three agents protected against the cigarette smoke effect. Heat inactivated catalase or superoxide dismutase was not protective. These observations indicate that active oxygen species, probably derived from the cig
arette smoke, play a role in smoke-mediated fiber transport into tracheobronchial epithelia."</p>
<p>If you found any of these excerpts interesting, please read the studies in their entirety. We all owe a debt of gratitude to these researchers for their hard work.</p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
marți, 7 mai 2013
Bluetick Coonhound Dog Breed
<p>Description: The Bluetick Coonhound breed has a broad head with a domed skull. Here we see the muzzle that is square long, deep, broad and has a predominant stop. This breed has round eyes, which are dark brown and widely set.</p>
<p>This breed has low ears, and these are thin. The tail is high, tapering to a beautiful point. The legs are straight, from the elbow; we see feet that are compact, with well arched toes. The hind legs are long and muscular. Their coats are glossy and smooth, dense and short, feeling slightly coarse to the touch.</p><p>The colours of this breed are dark blue, with thick mottled body, spotted with shapes of black spots on the back, we see this on the back, sides, and ears. The tricolour coat as a speckled blue to look at, its heavy ticking is in point of fact made up of black coloured hairs on a white background, which creates a blueing effect. Ears and head are principally black.</p><p>This breed can come with tan or without tan markings. If they appear, they should be on the chest, cheeks, and eyes and below the tail. If your dog has tan markings then you should see red ticking on feet and lower legs. Some standards prefer a more blue and black on the dog's body, at all tim
es there needs to be more blue ticking than white.</p><p>History: Here we have the state dog of Tennessee. It is said to have come from selective breeding, in Louisiana of the foxhounds, English Coonhound and curs. This breed has a very strong instinct to tree animals, this means scenting out the animal and chasing them literally at the tree. Raccoons live in all states of America, and have been pursued by hunters with the help of the Bluetick Coonhound.</p>
<p>The dog is expected to find, trail and tree the raccoons. Due to the fact that each dog has its own unique bark, which sounds more like a bay cry, night hunting with these dogs' is often used, as the hunter can follow the sound made by each individual dog.</p><p>Temperament: This breed is very intelligent and is exceptionally devoted to his family. It does well living outdoors, and is a good guardian to the family and home. This dog needs strong leadership, with firm handling, showing the owner as pack leader. Socialising this dog, whilst young, will avoid lots of problems with strangers and other dogs.</p><p>This dog is a hunter and is fervent about it; there should be no trust in this dog with other non-canine pets. Here we see an extremely alert and active dog, able to work over difficult terrain, and in any weather. This is not a dog to take off the lead, as his natural instincts will take over, and he will be off on the hunt. These dogs are usually best with older chi
ldren.</p><p>Health issues: This breed is prone to hit dyspepsia, Krabbe disease, and cataracts.</p><p>Grooming: This dog is low maintenance only needing an occasional brushing. Regular attention to the ears is a must, to prevent infection.</p><p>Living conditions: This is not an apartment dog. They will do best in a large garden that is secure and well fenced, this is due to the fact that they catch in the Wind scents and may wish to follow.</p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
<p>This breed has low ears, and these are thin. The tail is high, tapering to a beautiful point. The legs are straight, from the elbow; we see feet that are compact, with well arched toes. The hind legs are long and muscular. Their coats are glossy and smooth, dense and short, feeling slightly coarse to the touch.</p><p>The colours of this breed are dark blue, with thick mottled body, spotted with shapes of black spots on the back, we see this on the back, sides, and ears. The tricolour coat as a speckled blue to look at, its heavy ticking is in point of fact made up of black coloured hairs on a white background, which creates a blueing effect. Ears and head are principally black.</p><p>This breed can come with tan or without tan markings. If they appear, they should be on the chest, cheeks, and eyes and below the tail. If your dog has tan markings then you should see red ticking on feet and lower legs. Some standards prefer a more blue and black on the dog's body, at all tim
es there needs to be more blue ticking than white.</p><p>History: Here we have the state dog of Tennessee. It is said to have come from selective breeding, in Louisiana of the foxhounds, English Coonhound and curs. This breed has a very strong instinct to tree animals, this means scenting out the animal and chasing them literally at the tree. Raccoons live in all states of America, and have been pursued by hunters with the help of the Bluetick Coonhound.</p>
<p>The dog is expected to find, trail and tree the raccoons. Due to the fact that each dog has its own unique bark, which sounds more like a bay cry, night hunting with these dogs' is often used, as the hunter can follow the sound made by each individual dog.</p><p>Temperament: This breed is very intelligent and is exceptionally devoted to his family. It does well living outdoors, and is a good guardian to the family and home. This dog needs strong leadership, with firm handling, showing the owner as pack leader. Socialising this dog, whilst young, will avoid lots of problems with strangers and other dogs.</p><p>This dog is a hunter and is fervent about it; there should be no trust in this dog with other non-canine pets. Here we see an extremely alert and active dog, able to work over difficult terrain, and in any weather. This is not a dog to take off the lead, as his natural instincts will take over, and he will be off on the hunt. These dogs are usually best with older chi
ldren.</p><p>Health issues: This breed is prone to hit dyspepsia, Krabbe disease, and cataracts.</p><p>Grooming: This dog is low maintenance only needing an occasional brushing. Regular attention to the ears is a must, to prevent infection.</p><p>Living conditions: This is not an apartment dog. They will do best in a large garden that is secure and well fenced, this is due to the fact that they catch in the Wind scents and may wish to follow.</p><br><br><br><br><a href="http://iautoblog.com">iAutoblog</a> the premier <a href="http://iautoblog.com">autoblogger</a> software
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